2,570 research outputs found
Pure-glue hidden valleys through the Higgs portal
We consider the possibility that the Higgs boson can act as a link to a
hidden sector in the context of pure-glue hidden valley models. In these models
the standard model is weakly coupled, through loops of heavy messengers fields,
to a hidden sector whose low energy dynamics is described by a pure-Yang-Mills
theory. Such a hidden sector contains several metastable hidden glueballs. In
this work we shall extend earlier results on hidden valleys to include
couplings of the messengers to the standard model Higgs sector. The effective
interactions at one-loop couple the hidden gluons to the standard model
particles through the Higgs sector. These couplings in turn induce hidden
glueball decays to fermion pairs, or cascade decays with multiple Higgs
emission. The presence of effective operators of different mass dimensions,
often competing with each other, together with a great diversity of states,
leads to a great variability in the lifetimes and decay modes of the hidden
glueballs. We find that most of the operators considered in this paper are not
heavily constrained by precision electroweak physics, therefore leaving plenty
of room in the parameter space to be explored by the future experiments at the
LHC.Comment: 44 pages, 16 figures. Major revision for JHEP, corrected an error in
Eq. 5.1, comments adde
Ultrafast control of donor-bound electron spins with single detuned optical pulses
The ability to control spins in semiconductors is important in a variety of
fields including spintronics and quantum information processing. Due to the
potentially fast dephasing times of spins in the solid state [1-3], spin
control operating on the picosecond or faster timescale may be necessary. Such
speeds, which are not possible to attain with standard electron spin resonance
(ESR) techniques based on microwave sources, can be attained with broadband
optical pulses. One promising ultrafast technique utilizes single broadband
pulses detuned from resonance in a three-level Lambda system [4]. This
attractive technique is robust against optical pulse imperfections and does not
require a fixed optical reference phase. Here we demonstrate the principle of
coherent manipulation of spins theoretically and experimentally. Using this
technique, donor-bound electron spin rotations with single-pulse areas
exceeding pi/4 and two-pulses areas exceeding pi/2 are demonstrated. We believe
the maximum pulse areas attained do not reflect a fundamental limit of the
technique and larger pulse areas could be achieved in other material systems.
This technique has applications from basic solid-state ESR spectroscopy to
arbitrary single-qubit rotations [4, 5] and bang-bang control[6] for quantum
computation.Comment: 15 pages, 4 figures, submitted 12/2008. Since the submission of this
work we have become aware of related work: J. Berezovsky, M. H. Mikkelsen, N.
G. Stoltz, L. A. Coldren, and D. D. Awschalom, Science 320: 349-352 (2008
The Impact of a 4th Generation on Mixing and CP Violation in the Charm System
We study D0-D0 mixing in the presence of a fourth generation of quarks. In
particular, we calculate the size of the allowed CP violation which is found at
the observable level well beyond anything possible with CKM dynamics. We
calculate the semileptonic asymmetry a_SL and the mixing induced CP asymmetry
eta_fS_f which are correlated with each other. We also investigate the
correlation of eta_fS_f with a number of prominent observables in other mesonic
systems like epsilon'/epsilon, Br(K_L -> pi0 nu nu), Br(K+ -> pi+ nu nu),
Br(B_s ->mu+ mu-), Br(B_d -> mu+ mu-) and finally S_psi phi in the B_s system.
We identify a clear pattern of flavour and CP violation predicted by the SM4
model: While simultaneous large 4G effects in the K and D systems are possible,
accompanying large NP effects in the B_d system are disfavoured. However this
behaviour is not as pronounced as found for the LHT and RSc models. In contrast
to this, sizeable CP violating effects in the B_s system are possible unless
extreme effects in eta_fS_f are found, and Br(B_s ->mu+ mu-) can be strongly
enhanced regardless of the situation in the D system. We find that, on the
other hand, S_psi phi > 0.2 combined with the measured epsilon'/epsilon
significantly diminishes 4G effects within the D system.Comment: 22 pages, 23 figures, v2 (references added
Human cerebral malaria and Plasmodium falciparum genotypes in Malawi
<p>Abstract</p> <p>Background</p> <p>Cerebral malaria, a severe form of <it>Plasmodium falciparum </it>infection, is an important cause of mortality in sub-Saharan African children. A Taqman 24 Single Nucleotide Polymorphisms (SNP) molecular barcode assay was developed for use in laboratory parasites which estimates genotype number and identifies the predominant genotype.</p> <p>Methods</p> <p>The 24 SNP assay was used to determine predominant genotypes in blood and tissues from autopsy and clinical patients with cerebral malaria.</p> <p>Results</p> <p>Single genotypes were shared between the peripheral blood, the brain, and other tissues of cerebral malaria patients, while malaria-infected patients who died of non-malarial causes had mixed genetic signatures in tissues examined. Children with retinopathy-positive cerebral malaria had significantly less complex infections than those without retinopathy (OR = 3.7, 95% CI [1.51-9.10]).The complexity of infections significantly decreased over the malaria season in retinopathy-positive patients compared to retinopathy-negative patients.</p> <p>Conclusions</p> <p>Cerebral malaria patients harbour a single or small set of predominant parasites; patients with incidental parasitaemia sustain infections involving diverse genotypes. Limited diversity in the peripheral blood of cerebral malaria patients and correlation with tissues supports peripheral blood samples as appropriate for genome-wide association studies of parasite determinants of pathogenicity.</p
String Theory on Warped AdS_3 and Virasoro Resonances
We investigate aspects of holographic duals to time-like warped AdS_3
space-times--which include G\"odel's universe--in string theory. Using
worldsheet techniques similar to those that have been applied to AdS_3
backgrounds, we are able to identify space-time symmetry algebras that act on
the dual boundary theory. In particular, we always find at least one Virasoro
algebra with computable central charge. Interestingly, there exists a dense set
of points in the moduli space of these models in which there is actually a
second commuting Virasoro algebra, typically with different central charge than
the first. We analyze the supersymmetry of the backgrounds, finding related
enhancements, and comment on possible interpretations of these results. We also
perform an asymptotic symmetry analysis at the level of supergravity, providing
additional support for the worldsheet analysis.Comment: 24 pages + appendice
Effective-Range Expansion of the Neutron-Deuteron Scattering Studied by a Quark-Model Nonlocal Gaussian Potential
The S-wave effective range parameters of the neutron-deuteron (nd) scattering
are derived in the Faddeev formalism, using a nonlocal Gaussian potential based
on the quark-model baryon-baryon interaction fss2. The spin-doublet low-energy
eigenphase shift is sufficiently attractive to reproduce predictions by the
AV18 plus Urbana three-nucleon force, yielding the observed value of the
doublet scattering length and the correct differential cross sections below the
deuteron breakup threshold. This conclusion is consistent with the previous
result for the triton binding energy, which is nearly reproduced by fss2
without reinforcing it with the three-nucleon force.Comment: 21 pages, 6 figures and 6 tables, submitted to Prog. Theor. Phy
Ligand substitution reactions of a phenolic quinolyl hydrazone; oxidovanadium (IV) complexes
<p>Abstract</p> <p>Background</p> <p>Quinoline ring has therapeutic and biological activities. Quinolyl hydrazones constitute a class of excellent chelating agents. Recently, the physiological and biological activities of quinolyl hydrazones arise from their tendency to form metal chelates with transition metal ions. In this context, we have aimed to study the competency effect of a phenolic quinolyl hydrazone (H<sub>2</sub>L; primary ligand) with some auxiliary ligands (Tmen, Phen or Oxine; secondary ligands) towards oxidovanadium (IV) ions.</p> <p>Results</p> <p>Mono- and binuclear oxidovanadium (IV) - complexes were obtained from the reaction of a phenolic quinolyl hydrazone with oxidovanadium (IV)- ion in absence and presence of N,N,N',N'- tetramethylethylenediamine (Tmen), 1,10-phenanthroline (Phen) or 8-hydroxyquinoline (Oxine). The phenolic quinolyl hydrazone ligand behaves as monobasic bidentate (NO- donor with O- bridging). All the obtained complexes have the preferable octahedral geometry except the oxinato complex (<b>2</b>) which has a square pyramid geometry with no axial interaction; the only homoleptic complex in this study.</p> <p>Conclusion</p> <p>The ligand exchange (substitution/replacement) reactions reflect the strong competency power of the auxiliary aromatic ligands (Phen/Oxine) compared to the phenolic quinolyl hydrazone (H<sub>2</sub>L) towards oxidovanadium (IV) ion; (complexes <b>2 </b>and <b>3</b>). By contrast, in case of the more flexible aliphatic competitor (Tmen), an adduct was obtained (<b>4</b>). The obtained complexes reflect the strength of the ligand field towards the oxidovanadium (IV)- ion; Oxine or Phen >> phenolic hydrazone (H<sub>2</sub>L) > Tmen.</p
End points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain
To address the global burden of sickle cell disease (SCD) and the need for novel therapies, the American Society of Hematology partnered with the US Food and Drug Administration to engage the work of 7 panels of clinicians, investigators, and patients to develop consensus recommendations for clinical trial end points. The panels conducted their work through literature reviews, assessment of available evidence, and expert judgment focusing on end points related to: patient-reported outcomes (PROs), pain (non-PROs), the brain, end-organ considerations, biomarkers, measurement of cure, and low-resource settings. This article presents the findings and recommendations of the PROs, pain, and brain panels, as well as relevant findings and recommendations from the biomarkers panel. The panels identify end points, where there were supporting data, to use in clinical trials of SCD. In addition, the panels discuss where further research is needed to support the development and validation of additional clinical trial end points
State-space Manifold and Rotating Black Holes
We study a class of fluctuating higher dimensional black hole configurations
obtained in string theory/ -theory compactifications. We explore the
intrinsic Riemannian geometric nature of Gaussian fluctuations arising from the
Hessian of the coarse graining entropy, defined over an ensemble of brane
microstates. It has been shown that the state-space geometry spanned by the set
of invariant parameters is non-degenerate, regular and has a negative scalar
curvature for the rotating Myers-Perry black holes, Kaluza-Klein black holes,
supersymmetric black holes, - configurations and the
associated BMPV black holes. Interestingly, these solutions demonstrate that
the principal components of the state-space metric tensor admit a positive
definite form, while the off diagonal components do not. Furthermore, the ratio
of diagonal components weakens relatively faster than the off diagonal
components, and thus they swiftly come into an equilibrium statistical
configuration. Novel aspects of the scaling property suggest that the
brane-brane statistical pair correlation functions divulge an asymmetric
nature, in comparison with the others. This approach indicates that all above
configurations are effectively attractive and stable, on an arbitrary
hyper-surface of the state-space manifolds. It is nevertheless noticed that
there exists an intriguing relationship between non-ideal inter-brane
statistical interactions and phase transitions. The ramifications thus
described are consistent with the existing picture of the microscopic CFTs. We
conclude with an extended discussion of the implications of this work for the
physics of black holes in string theory.Comment: 44 pages, Keywords: Rotating Black Holes; State-space Geometry;
Statistical Configurations, String Theory, M-Theory. PACS numbers: 04.70.-s
Physics of black holes; 04.70.Bw Classical black holes; 04.70.Dy Quantum
aspects of black holes, evaporation, thermodynamics; 04.50.Gh
Higher-dimensional black holes, black strings, and related objects. Edited
the bibliograph
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